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Heart Specialty Center
Cardiac clinical trials
St. Anthony’s physicians and staff regularly work with patients who opt to participate in clinical trials designed to test the effects of medications, medical devices and care protocols in the treatment of heart disorders and diseases. All clinical trials are overseen by a cardiologist or cardiovascular surgeon, approved by the Institutional Review Board and coordinated by a Clinical Research Coordinator.
Ongoing and upcoming clinical research trials:
FREEDOM Registry Study: A Registry study that documents any cardiac and neurological events occurring in patients undergoing a Carotid artery stenting procedure performed with the GORE Flow Reversal System and the GORE Distal Protection System in patients with carotid artery stenosis. The study follows the patient for 30 days to detect any neurological problems post stenting procedure.
Abbott BL01 Trial: A study with an Investigational Nutritional Supplement with AN777 versus Control Nutritional Supplement in patients with Myocardial Infarction, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease and Pneumonia. The Investigational Nutritional Supplement with AN777 is formulated to increase lean muscle mass, improve overall health and decrease patient re-hospitalization rates. Patients ingest two packages of the nutritional supplement each day for 90 days and are followed for any occurrence of re-hospitalizations, morbid events and hospital care consumption.
EUCLID Study: A study of Ticagrelor, which is already approved for use in cardiac patients, versus Clopidogrel in patients with peripheral vascular disease to decrease the occurrence of major cardiovascular events such as any cardiovascular occurrence, stroke, and myocardial infarction. Patients will be followed every 4 months the first year and every 6 months after that for up to 36 months.
ACP Trial: A study using the Amplatzer Cardiac Plug versus standard of care anticoagulation in patients with atrial fibrillation. The Amplatzer Cardiac Plug is placed in the left atrial appendage to occlude the appendage and trap any blood clots to keep them from going out into the body. This will decrease the risk of strokes occurring for patients with atrial fibrillation. Patients will be followed up to 2 years to assess the device placement success with Trans-esophageal echocardiograms and physical exams and to follow for occurrence of any events.
ODYSSEY Study: A study with an investigational injectable monoclonal antibody versus placebo in patients with acute coronary syndrome. The investigational injectable monoclonal antibody is intended to decrease LDL cholesterol and risks for cardiovascular events. Patients will be treated and followed for 64 months to cardiac events, stroke and heart related re-hospitalizations.
For information about these and other clinical trials at St. Anthony’s, please contact our Clinical Research Coordinator at 314-525-1697
For information, please call our Health Access Line at 314-ANTHONY (268-4669) or 800-554-9550 or visit find a physician online.
Working as trusted partners, the physicians and employees of St. Anthony's Health System will deliver care distinguished by its demonstrated quality and personalized service. We will be visibly engaged in improving the health and well being of the communities we serve in South County and beyond. We will stand together, proud to set the standard for independent community health systems.